Invitrogen™ CD52 Chimeric Recombinant Mouse Monoclonal Antibody (YTH 34.5-G2b (Campath-1G))

Mouse Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547806

Catalog No. PIMA547806

Description

Specificity: Human CD52 antigen, also known as CAMPATH-1. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.

CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.

Specifications

• Antigen: CD52 Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P31358, P32763
• Gene Symbols: CD52
• Immunogen: Human peripheral mononuclear cells enriched for T-cells.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human, Rhesus Macaque, Cynomolgus Monkey
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Cytotoxicity Assay, ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: YTH 34.5-G2b (Campath-1G)
• Conjugate: Unconjugated
• Gene: CD52
• Gene Alias: AI463198; B7; B7-Ag; cambridge pathology 1 antigen; CAMPATH-1; CAMPATH-1 antigen; Cd52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CD52 molecule; CDW52; CDW52 antigen (CAMPATH-1 antigen); CLS1; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; HEL-S-171mP; human epididymis-specific protein 5; Lymphocyte differentiation antigen B7; Mb7
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 102144354, 1043, 714429
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid