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Invitrogen™ CD52 Monoclonal Antibody (HI186), APC
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Catalog No. PIMA110245
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100 Tests
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Catalog No. Quantity
PIMA110245 100 Tests
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Catalog No. PIMA110245 Supplier Invitrogen™ Supplier No. MA110245
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Description

Mouse Monoclonal Antibody

This antibody reacts with CD52 (CAMPATH-1), a 21-28 kDa extracellular glycoprotein containing a large N-linked carbohydrate moiety; mature CD52 molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, monocytes/macrophages and in male reproductive tract.

CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD52
Applications Flow Cytometry
Classification Monoclonal
Clone HI186
Concentration 0.7 mg/mL
Conjugate APC
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene CD52
Gene Accession No. P31358
Gene Alias AI463198; B7; B7-Ag; cambridge pathology 1 antigen; CAMPATH-1; CAMPATH-1 antigen; Cd52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CD52 molecule; CDW52; CDW52 antigen (CAMPATH-1 antigen); CLS1; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; HEL-S-171mP; human epididymis-specific protein 5; Lymphocyte differentiation antigen B7; Mb7
Gene Symbols CD52
Host Species Mouse
Immunogen Human tonsil.
Purification Method Size-exclusion chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1043
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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Safety and Handling

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