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Invitrogen™ CD52 Monoclonal Antibody (YTH34.5)
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Catalog No. PIMA516999
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500 μg
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PIMA516999 500 μg
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Catalog No. PIMA516999 Supplier Invitrogen™ Supplier No. MA516999
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Description

Rat Monoclonal Antibody

This product is a low-endotoxin, preservative-free formulation. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. A suggested positive control for immunohistochemical applications is tonsil. For cytotoxic assays, use human serum as a complement source. Rat anti Human CD52 antibody, clone YTH34.5 reacts with the human CD52 antigen, also known as CAMPATH-1.

CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD52
Applications Cytotoxicity Assay, ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone YTH34.5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CD52
Gene Accession No. P31358
Gene Alias AI463198; B7; B7-Ag; cambridge pathology 1 antigen; CAMPATH-1; CAMPATH-1 antigen; Cd52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CD52 molecule; CDW52; CDW52 antigen (CAMPATH-1 antigen); CLS1; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; HEL-S-171mP; human epididymis-specific protein 5; Lymphocyte differentiation antigen B7; Mb7
Gene Symbols CD52
Host Species Rat
Immunogen human lymphocytes.
Purification Method Protein A
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1043, 714429
Target Species Human, Rhesus Macaque
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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