Invitrogen™ CD52 Monoclonal Antibody (YTH34.5), FITC

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA517000	Invitrogen™ MA517000	100 μg
PIMA517001	Invitrogen™ MA517001	25 μg

Description

For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Rat anti Human CD52 antibody, clone YTH34.5 reacts with the human CD52 antigen, also known as CAMPATH-1. Rat anti Human CD52 antibody, clone YTH34.5 reacts with the human CD52 antigen, also known as CAMPATH-1.

CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.

Specifications

• Antigen: CD52
• Concentration: 0.1 mg/mL
• Applications: Flow Cytometry
• Conjugate: FITC
• Host Species: Rat
• Regulatory Status: RUO
• Formulation: PBS with 1% BSA and 0.09% sodium azide
• Gene Accession No.: P31358
• Gene ID (Entrez): 1043, 714429
• Immunogen: human lymphocytes.
• Product Type: Antibody

• Clone: YTH34.5
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG2b
• Target Species: Human, Rhesus Macaque
• Gene: CD52
• Gene Alias: AI463198; B7; B7-Ag; cambridge pathology 1 antigen; CAMPATH-1; CAMPATH-1 antigen; Cd52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CD52 molecule; CDW52; CDW52 antigen (CAMPATH-1 antigen); CLS1; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; HEL-S-171mP; human epididymis-specific protein 5; Lymphocyte differentiation antigen B7; Mb7
• Gene Symbols: CD52
• Primary or Secondary: Primary
• Purification Method: Protein A