Invitrogen™ CD52 Monoclonal Antibody (YTH34.5)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA516999

Catalog No. PIMA516999

Description

This product is a low-endotoxin, preservative-free formulation. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. A suggested positive control for immunohistochemical applications is tonsil. For cytotoxic assays, use human serum as a complement source. Rat anti Human CD52 antibody, clone YTH34.5 reacts with the human CD52 antigen, also known as CAMPATH-1.

CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.

Specifications

• Antigen: CD52
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P31358
• Gene Symbols: CD52
• Immunogen: human lymphocytes.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human, Rhesus Macaque
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Cytotoxicity Assay, ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: YTH34.5
• Conjugate: Unconjugated
• Gene: CD52
• Gene Alias: AI463198; B7; B7-Ag; cambridge pathology 1 antigen; CAMPATH-1; CAMPATH-1 antigen; Cd52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CD52 molecule; CDW52; CDW52 antigen (CAMPATH-1 antigen); CLS1; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; HEL-S-171mP; human epididymis-specific protein 5; Lymphocyte differentiation antigen B7; Mb7
• Host Species: Rat
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1043, 714429
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid