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Invitrogen™ CD53 Monoclonal Antibody (1H2C7)
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Catalog No. FERMA548414
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100 μg
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Catalog No. Quantity
FERMA548414 100 μg
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Catalog No. FERMA548414 Supplier Invitrogen™ Supplier No. MA548414
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Description

Mouse Monoclonal Antibody

CD53 Monoclonal Antibody for Western Blot, IHC (P), Flow, ELISA

CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumor cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD53
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Classification Monoclonal
Clone 1H2C7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Cd53
Gene Accession No. P19397
Gene Alias AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; Cd53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; cell surface glycoprotein CD53; Leukocyte antigen MRC OX-44; leukocyte surface antigen CD53; MOX44; OX44; Ox-44; tetraspanin-25; transmembrane glycoprotein; TSPAN25; tspan-25
Gene Symbols Cd53
Host Species Mouse
Immunogen Purified recombinant fragment of human CD53 (AA: extra mix) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 963
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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