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CD53 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983033
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100 μL
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Catalog No. Quantity
50-198-3033 100 μL
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Catalog No. 50-198-3033 Supplier Bioss Supplier No. BS13625R
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Description

Rabbit Polyclonal Antibody

CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumor cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.

Specifications

Antigen CD53
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Cd53
Gene Accession No. P19397
Gene Alias AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; Cd53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; Cell surface glycoprotein CD53; EGM_00928; hypothetical protein; Leukocyte antigen MRC OX-44; Leukocyte surface antigen CD53; MOX44; OX44; Ox-44; Tetraspanin-25; transmembrane glycoprotein; TSPAN25; Tspan-25
Gene Symbols Cd53
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CD53.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 963
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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