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BD Horizon™ CD54 (ICAM-1) Mouse, anti-Human, RY586, Clone: HA58, BD Horizon™
Shop All BD Biosciences ProductsDescription
The HA58 monoclonal antibody specifically binds to CD54 which is also known as ICAM-1 (intracellular adhesion molecule-1). CD54 is an 85-110 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin supergene family. A soluble form of CD54 can also be found in biological fluids. CD54 is expressed on endothelial cells and both resting (weak) and activated (moderate) lymphocytes and monocytes. CD54 is a ligand for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). The CD54 adhesion molecule plays roles in inflammatory and immune responses and neoplasia. This antibody (NA/LE format) blocks the mixed-lymphocyte reaction (MLR) and the purified format is suitable for staining acetone-fixed, frozen tissue sections.
Specifications
Specifications
| Antigen | CD54 (ICAM-1) |
| Applications | Flow Cytometry |
| Clone | HA58 |
| Conjugate | RY586 |
| Host Species | Mouse |
| Quantity | 100 Tests |
| Regulatory Status | RUO |
| Primary or Secondary | Primary |
| Target Species | Human |
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