CD54 Mouse anti-Human, APC, Clone: HA58, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB561899	BD Biosciences 561899	25 Tests
BDB559771	BD Biosciences 559771	100 Tests

Description

The HA58 monoclonal antibody specifically binds to CD54 which is also known as ICAM-1 (intracellular adhesion molecule-1). CD54 is an 85-110 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin supergene family. A soluble form of CD54 can also be found in biological fluids. CD54 is expressed on endothelial cells and both resting (weak) and activated (moderate) lymphocytes and monocytes. CD54 is a ligand for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). The CD54 adhesion molecule plays roles in inflammatory and immune responses and neoplasia. This antibody (NA/LE format) blocks the mixed-lymphocyte reaction (MLR) and the purified format is suitable for staining acetone-fixed, frozen tissue sections.

Specifications

• Antigen: CD54
• Applications: Flow Cytometry
• Conjugate: APC
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: ICAM-1; intercellular adhesion molecule 1; BB2; P3.58

• Clone: HA58
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Immunogen: IFN-γ-treated BM314 colonic carcinoma cells
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.