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CD54 Mouse anti-Human, PE, Clone: HA58, BD

Catalog No. BDB560971 Shop All BD Biosciences Products
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BDB560971 25 Tests
BDB555511 100 Tests
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Description

Mouse Monoclonal Antibody

The HA58 monoclonal antibody specifically binds to CD54 which is also known as ICAM-1 (intracellular adhesion molecule-1). CD54 is an 85-110 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin supergene family. A soluble form of CD54 can also be found in biological fluids. CD54 is expressed on endothelial cells and both resting (weak) and activated (moderate) lymphocytes and monocytes. CD54 is a ligand for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). The CD54 adhesion molecule plays roles in inflammatory and immune responses and neoplasia. This antibody (NA/LE format) blocks the mixed-lymphocyte reaction (MLR) and the purified format is suitable for staining acetone-fixed, frozen tissue sections.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD54
Applications Flow Cytometry
Classification Monoclonal
Clone HA58
Conjugate PE
Description ICAM-1; intercellular adhesion molecule 1; BB2; P3.58
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen IFN-γ-treated BM314 colonic carcinoma cells
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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