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CD56 Monoclonal Antibody (C5.9), FITC, Invitrogen™

Catalog No. 01670863
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100 Tests
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Catalog No. Quantity
01-670-863 100 Tests
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Catalog No. 01-670-863 Supplier Thermo Scientific Supplier No. MA112144

Description

Mouse Monoclonal Antibody

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD56
Applications Flow Cytometry
Classification Monoclonal
Clone C5.9
Concentration 0.025 mg/mL
Conjugate FITC
Formulation PBS with 0.2% carrier protein and 0.08% sodium azide
Gene Ncam1
Gene Accession No. P13591
Gene Alias adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Gene Symbols Ncam1
Host Species Mouse
Immunogen human cell line KG-1a
Purification Method purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4684
Target Species Human
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b
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