Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ CD56 (NCAM) Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142752

Catalog No. PIPA5142752


Only null left
Add to Cart
This item is not returnable. View return policy

Description

Description

Additional Information: This antibody is expected to recognize reported isoform 2 (NP_851996.2) only. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD56 (NCAM)
Polyclonal
Unconjugated
Ncam1
adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Goat
Ammonium sulfate precipitation
RUO
4684
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
P13591
Ncam1
Peptide with sequence C-KASWTRPEKQETLD (aa 353-366).
100 μg
Primary
Human
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.