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CD58 Mouse, anti-Human, R718, Clone: 1C3, BD OptiBuild™

Catalog No. BDB752136 Shop All BD Biosciences Products
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BDB752136 50 μg
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Catalog No. BDB752136 Supplier BD Biosciences Supplier No. 752136
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Description

Mouse Monoclonal Antibody

The 1C3 (AICD58.6) monoclonal antibody specifically binds to CD58. CD58 is a a 60-70 kDa glycoprotein member of the immunoglobulin superfamily. CD58, also referred to as the lymphocyte function-associated antigen-3 (LFA-3), has a wide tissue distribution, being expressed on both hematopoietic and non-hematopoietic cells, including endothelial cells and fibroblasts. There are two isoforms of CD58: a glycosylphosphatidylinositol (GPI)-linked form and a transmembrane form. Both isoforms may be expressed on the same cell type. Erythrocytes, however, only express the GPI-linked isoform. CD58 interacts with CD2 during cell adhesion. This binding can enhance antigen-specific T-cell activation. This interaction can also play a role in cell-mediated cytotoxicity.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD58
Applications Flow Cytometry
Classification Monoclonal
Clone 1C3
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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