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  6. CD59 Mouse anti-Human, PE, Clone: P282 (H19), BD

CD59 Mouse anti-Human, PE, Clone: P282 (H19), BD

Catalog No. BDB560953 Shop All BD Biosciences Products
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BDB560953 25 Tests
BDB555764 100 Tests
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Catalog No. BDB560953 Supplier BD Biosciences Supplier No. 560953
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Description

Mouse Monoclonal Antibody

The p282 (HI9) monoclonal antibody specifically binds to CD59, a 19 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein, expressed on hematopoietic and non-hematopoietic cells. Because of its role in interaction with complement activated products, CD59 has been termed membrane-attack-complex-inhibitory factor (MACIF), homologus restriction factor (HRF20), membrane inhibitor of reactive lysis (MIRL) and Protectin. It inhibits the cytolytic activity of complement by binding to C8 and C9, thereby blocking the assembly of the membrane attack complex. CD59 also participates in spontaneous T-cell/erythrocyte adhesion, interacts with CD2 and plays a role in T-cell activation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD59
Applications Flow Cytometry
Classification Monoclonal
Clone p282 (H19)
Conjugate PE
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Erythrocytes
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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