CD5L/Api6 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS2487R

Catalog No. 50-198-4763

Description

Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.

Specifications

• Antigen: CD5L/Api6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cd5l
• Gene Alias: 1/6; AAC-11; AI047839; Aim; AIM/Spalpha; API6; apoptosis inhibitor 6; Apoptosis inhibitor expressed by macrophages; apoptosis inhibitor of macrophage; Apoptosis inhibitory 6; CD5 antigen-like; CD5 antigen-like (scavenger receptor cysteine rich family); CD5 molecule like; CD5 molecule-like; CD5L; CT2; CT-2; hAIM; IgM-associated peptide; mAIM; Pdp; Pdp 1/6; PRO229; Spalpha; SP-alpha; UNQ203/PRO229
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 922
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: O43866
• Gene Symbols: Cd5l
• Immunogen: KLH conjugated synthetic peptide derived from human CD5L.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG