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Invitrogen™ CD6 Monoclonal Antibody (6B9)
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Catalog No. PIMA517047
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100 μg
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Catalog No. Quantity
PIMA517047 100 μg
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Catalog No. PIMA517047 Supplier Invitrogen™ Supplier No. MA517047
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Description

Mouse Monoclonal Antibody

MA5-17047 targets CD6 in IHC, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17047 immunogen is purified recombinant fragment of human CD6 (amino acids: 472-668) expressed in E. Coli. MA5-17047 detects CD6 which has a predicted molecular weight of approximately 71.8kDa.

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD6
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 6B9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene CD6
Gene Accession No. P30203
Gene Alias Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
Gene Symbols CD6
Host Species Mouse
Immunogen Purified recombinant fragment of human CD6 (amino acids: 472-668) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 923
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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