Invitrogen™ CD6 Monoclonal Antibody (6B9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA517047

Catalog No. PIMA517047

Description

MA5-17047 targets CD6 in IHC, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17047 immunogen is purified recombinant fragment of human CD6 (amino acids: 472-668) expressed in E. Coli. MA5-17047 detects CD6 which has a predicted molecular weight of approximately 71.8kDa.

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.

Specifications

• Antigen: CD6
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P30203
• Gene Symbols: CD6
• Immunogen: Purified recombinant fragment of human CD6 (amino acids: 472-668) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 6B9
• Conjugate: Unconjugated
• Gene: CD6
• Gene Alias: Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 923
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid