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Invitrogen™ CD6 Monoclonal Antibody (MEM-98), FITC
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Catalog No. PIMA528095
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100 μg
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PIMA528095 100 μg
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Catalog No. PIMA528095 Supplier Invitrogen™ Supplier No. MA528095
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Description

Mouse Monoclonal Antibody

Mouse anti Human CD6 antibody, clone MEM-98 recognizes human CD6, also known as T12 or TP120.

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
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Specifications

Antigen CD6
Applications Flow Cytometry
Classification Monoclonal
Clone MEM-98
Concentration 100 μg/mL
Conjugate FITC
Formulation PBS with 1% BSA and 0.09% sodium azide
Gene CD6
Gene Accession No. P30203
Gene Alias Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
Gene Symbols CD6
Host Species Mouse
Immunogen Purified CD6 antigen.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 923
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Product Type Antibody
Form Liquid
Isotype IgG1
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