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CD6 Mouse, anti-Mouse, R718, Clone: J90-462, BD OptiBuild™

Catalog No. BDB751956 Shop All BD Biosciences Products
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BDB751956 50 μg
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Catalog No. BDB751956 Supplier BD Biosciences Supplier No. 751956
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Description

Mouse Monoclonal Antibody

The J90-462 monoclonal antibody specifically recognizes CD6. CD6 is a 105-130 kDa type I transmembrane glycoprotein that belongs to the scavenger receptor family. It is expressed on most thymocytes and peripheral T cells. CD6 is highly expressed on CD3-high thymocytes and expressed at lower levels on CD4+ CD8+ double positive and CD4+CD8- or CD4-CD8+ single positive thymocytes. CD6 is also reportedly expressed at low levels by some neurons. CD6 serves as a receptor for CD166, also known as Activated Leukocyte Cell Adhesion Molecule (ALCAM). CD6 plays a role in adhesion and migration during organogenesis. The CD6 intracellular domain is constitutively phosphorylated which suggests that CD6 may play a signaling role in T cell activation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD6
Applications Flow Cytometry
Classification Monoclonal
Clone J90-462
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Refrigerate Upon Arrival
Form Liquid
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