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Invitrogen™ CD6 Polyclonal Antibody
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Catalog No. PIPA5117117
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100 μL
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PIPA5117117 100 μL
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Catalog No. PIPA5117117 Supplier Invitrogen™ Supplier No. PA5117117
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Description

Rabbit Polyclonal Antibody

Positive Samples: MCF7, Jurkat, U-937, HT-29, Raji Immunogen sequence: LRIKGKYALP VMVNHQHLPT TIPAGSNSYQ PVPITIPKEV FMLPIQVQAP PPEDSDSGSD SDYEHYDFSA QPPVALTTFY NSQRHRVTDE EVQQSRFQMP PLEEGLEELH ASHIPTANPG HCITDPPSLG PQYHPRSNSE SSTSSGEDYC NSPKSKLPPW NPQVFSSERS SFLEQPPNLE LAGTQPAFSA GPPADDSSST SSGEWYQNFQ PPPQPPSEEQ FGCPGSPSPQ PDSTDNDDYD DISAA.

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD6
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CD6
Gene Accession No. P30203
Gene Alias Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
Gene Symbols CD6
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 424-668 of human CD6 (NP_0067163).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 923
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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