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CD6 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501731163 Shop All Proteintech Group Inc Products
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50-173-1163 150 μL
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Catalog No. 50-173-1163 Supplier Proteintech Group Inc Supplier No. 167631AP150UL
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Description

Rabbit Polyclonal Antibody

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.

Specifications

Antigen CD6
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CD6
Gene Accession No. P30203
Gene Alias CD6, CD6 molecule, T12, TP120
Gene Symbols CD6
Host Species Rabbit
Immunogen CD6 Fusion Protein Ag10336
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 923
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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