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CD61 (Integrin beta 3) Monoclonal Antibody (2C9.G3), NovaFluor™ Blue 690, eBioscience™, Invitrogen™

Catalog No. M053T02B09
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25 μg
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M053T02B09 25 μg
M053T03B09 100 μg
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Catalog No. M053T02B09 Supplier Invitrogen Supplier No. M053T02B09

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Armenian Hamster Monoclonal Antibody

CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectrin. CD61 is a 105 kDa glycoprotein that associates with either the alpha 11b integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, Von Willebrand Factor, vitronectin and thrombospondin. The CD61 protein product is composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. CD61 is found along with the alpha IIb chain in platelets. Like other integrins, CD61 is known to participate in cell adhesion as well as cell-surface mediated signaling. Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD61 (Integrin beta 3)
Applications Flow Cytometry
Classification Monoclonal
Clone 2C9.G3
Concentration 0.1 mg/mL
Conjugate NovaFluor Blue 690
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene ITGB3
Gene Accession No. O54890
Gene Alias antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa
Gene Symbols ITGB3
Host Species Armenian Hamster
Purification Method Affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16416, 29302
Target Species Mouse, Rat
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Form Liquid
Isotype IgG
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