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CD61 Mouse anti-Rat, FITC, Clone: F11, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 561909
Description
The F11 antibody reacts with the integrin β3 chain (CD61), which associates with the integrin αv chain (CD51), to form the vitronectin receptor found on endothelial cells, myeloid cells, and osteoclasts, and with the αIIb chain (CD41) on platelets and megakaryocytes. Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. F11 mAb has been reported to block the in vitro attachment of osteoclasts to several ligands. Weak reactivity with human osteoclasts, megakaryocytes, and platelets has also been reported.
Specifications
| CD61 | |
| Monoclonal | |
| 0.5mg/mL | |
| Integrin β3 chain | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Rat | |
| IgG1 κ |
| Flow Cytometry | |
| F11 | |
| FITC | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Rat (Sprague-Dawley) bone cell suspensions | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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