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CD61 Mouse anti-Rat, FITC, Clone: F11, BD

Catalog No. BDB561909 Shop All BD Biosciences Products
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0.5 mg
50 μg
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BDB561909 50 μg
BDB554952 0.5 mg
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Catalog No. BDB561909 Supplier BD Biosciences Supplier No. 561909
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Description

Mouse Monoclonal Antibody

The F11 antibody reacts with the integrin β3 chain (CD61), which associates with the integrin αv chain (CD51), to form the vitronectin receptor found on endothelial cells, myeloid cells, and osteoclasts, and with the αIIb chain (CD41) on platelets and megakaryocytes. Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. F11 mAb has been reported to block the in vitro attachment of osteoclasts to several ligands. Weak reactivity with human osteoclasts, megakaryocytes, and platelets has also been reported.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD61
Applications Flow Cytometry
Classification Monoclonal
Clone F11
Concentration 0.5mg/mL
Conjugate FITC
Description Integrin β3 chain
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Rat (Sprague-Dawley) bone cell suspensions
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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