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CD61 Mouse, anti-Rat, R718, Clone: F11, BD OptiBuild™

Catalog No. BDB752184 Shop All BD Biosciences Products
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BDB752184 50 μg
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Catalog No. BDB752184 Supplier BD Biosciences Supplier No. 752184
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Description

Mouse Monoclonal Antibody

The F11 monoclonal antibody specifically recognizes integrin β3 chain (CD61), which associates with the integrin αv chain (CD51), to form the vitronectin receptor found on endothelial cells, myeloid cells, and osteoclasts, and with the αIIb chain (CD41) on platelets and megakaryocytes. Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. The F11 antibody reportedly blocks the in vitro attachment of osteoclasts to several ligands. Weak F11 antibody reactivity with human osteoclasts, megakaryocytes, and platelets has also been reported.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD61
Applications Flow Cytometry
Classification Monoclonal
Clone F11
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Refrigerate Upon Arrival
Form Liquid
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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