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CD62P Mouse, anti-Human, R718, Clone: AK-4, BD OptiBuild™

Catalog No. BDB751983 Shop All BD Biosciences Products
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BDB751983 50 μg
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Catalog No. BDB751983 Supplier BD Biosciences Supplier No. 751983
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Description

Mouse Monoclonal Antibody

The AK-4 monoclonal antibody specifically binds to CD62P. CD62P is a 140 kDa type I transmembrane glycoprotein that is also known as P-Selectin, Platelet activation-dependent granule membrane protein (PADGEM), or Granule membrane protein-140 (GMP-140). CD62P is expressed by megakaryocytes, activated platelets and activated endothelium. P-Selectin is stored in the α-granules of platelets and the Weibel-Palade bodies of endothelial cells, and is rapidly transported to the plasma membrane upon activation. P-Selectin is thought to mediate the initial adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses, and of activated platelets to neutrophils and monocytes in hemostasis.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD62P
Applications Flow Cytometry
Classification Monoclonal
Clone AK-4
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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