CD63 Mouse anti-Human, PE, Clone: SPM524, Abnova™
Mouse monoclonal antibody raised against native human CD63.
Manufacturer: Abnova Corporation MAB13020
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq]
|Mouse monoclonal antibody raised against native human CD63.|
|In PBS (0.05% BSA, 0.05% sodium azide).|
|Store at 4°C.|
|Flow Cytometry, Immunofluorescence|
|Flow Cytometry (5 uL per test per one million cells in 0.1 mL) Immunofluorescence (1:50-1:100) The optimal working dilution should be determined by the end user.|
|Smooth plasma membrane fraction of MeWo cells.|
|Protein A/G purification|
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