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  6. CD64 Mouse anti-Human, Brilliant Ultraviolet 737, Clone: 10.1, BD Horizon™

CD64 Mouse anti-Human, Brilliant Ultraviolet 737, Clone: 10.1, BD Horizon™

Catalog No. BDB612776 Shop All BD Biosciences Products
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Catalog No. BDB612776 Supplier BD Biosciences Supplier No. 612776
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Description

Mouse Monoclonal Antibody

The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγhomodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.

Due to spectral differences between labeled cells and beads, using BD™ CompBeads can result in incorrect spillover values when used with BD Horizon BUV737 reagents. Therefore, the use of BD CompBeads or BD CompBeads Plus to determine spillover values for these reagents is not recommended. Different BUV737 reagents (e.g., CD4 vs. CD45) can have slightly different fluorescence spillover therefore, it may also be necessary to use clone specific compensation controls when using these reagents.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD64
Applications Flow Cytometry
Classification Monoclonal
Clone 10.1
Conjugate Brilliant Ultraviolet 737
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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