Invitrogen™ CD66 Recombinant Mouse Monoclonal Antibody (A5B7)

Catalog No.	Quantity
PIMA548180	200 μg

Catalog No. PIMA548180 Supplier Invitrogen™ Supplier No. MA548180

Description

Mouse Recombinant Monoclonal Antibody

Specificity: This antibody is specific for human CEA.

The CD66 molecules are 180-200 kDa glycoproteins of carcinoembryonic antigen family. They are present on all blood granulocytes and some tissue macrophages, but are absent from other hematopoietic cells. The expression of CD66 increases significantly on granulocytes upon their activation. CD66a (BGP1, CEACAM1) and CD66d (CGM1, CEACAM3), as well as CEACAM2 and 4, are transmembrane proteins, whereas CD66c (CEAL, NCA, CEACAM6) and CD66e (CEA, CEACAM5), as well as CEACAM7 and 8, are anchored to the plasma membrane by C-terminal glycosylphosphatidylinositol (GPI) lipid moiety.

Specifications

• Antigen: CD66
• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry, Radioimmune Assays (RIA), Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: A5B7
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% ProClin 300
• Gene: CEACAM1
• Gene Accession No.: O75871, P06731, P13688, P40198, P40199
• Gene Alias: antigen CD66; BGP; BGP1; BGP-1; BGPI; Biliary glycoprotein 1; Carcinoembryonic antigen; Carcinoembryonic antigen CGM1; carcinoembryonic antigen CGM7; carcinoembryonic antigen gene family member 1; carcinoembryonic antigen gene family member 7; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen related cell adhesion molecule 3; carcinoembryonic antigen related cell adhesion molecule 4; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); carcinoembryonic antigen-related cell adhesion molecule 3; Carcinoembryonic antigen-related cell adhesion molecule 4; carcinoembryonic antigen-related cell adhesion molecule 4-sv1; carcinoembryonic antigen-related cell adhesion molecule 4-sv2; carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66a; CD66a antigen; CD66c; CD66d; CD66d antigen; CD66e; CEA; CEACAM1; CEACAM-1; CEACAM3; CEACAM-3; CEACAM4; CEACAM5; CEACAM-5; CEACAM6; CEACAM-6; CEAL; CGM1; CGM7; CGM7_HUMAN; Cluster of Differentiation 66c; meconium antigen 100; NCA; Non-specific crossreacting antigen; nonspecific cross-reacting antigen; Nonspecific cross-reacting antigen (NCA); non-specific cross-reacting antigen W236; nonspecific cross-reacting antigen W236; normal cross-reacting antigen; pan CEACAM; W264; W282
• Gene Symbols: CEACAM1, CEACAM3, CEACAM4, CEACAM5, CEACAM6
• Host Species: Mouse
• Immunogen: This antibody was raised by immunising mice with both carcinoembryonic antigen (CEA) purified from the metastases of colonic tumours, and heat-treated CEA.
• Purification Method: Protein A
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1048, 1084, 1089, 4680, 634
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ