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  6. Invitrogen™ CD68 Monoclonal Antibody (FA-11), Alexa Fluor™ 488, eBioscience™, Invitrogen™ 

Invitrogen™ CD68 Monoclonal Antibody (FA-11), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Catalog No. 53068180
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53-068-180 25 μg
53-068-182 100 μg
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Catalog No. 53-068-180 Supplier Invitrogen™ Supplier No. 53068180
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Description

Rat Monoclonal Antibody

This FA-11 monoclonal antibody reacts with mouse CD68, known also as macrosialin. CD68 is a heavily O- and N- glycosylated type I integral membrane protein belonging to the sialomucin family and is closely related to the Lysosomal/endosomal-Associated Mem

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD68
Applications Flow Cytometry
Classification Monoclonal
Clone FA-11
Concentration 0.5 mg/mL
Conjugate Alexa Fluor 488
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Cd68
Gene Accession No. P31996
Gene Alias CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Gene Symbols Cd68
Host Species Rat
Purification Method Affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12514
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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