Invitrogen™ CD68 Monoclonal Antibody (KP1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA513324

Catalog No. PIMA513324

Description

MA5-13324 targets CD68 in IHC (P) and ICC/IF applications and shows reactivity with Feline, Human, Non-human primate, and Rat samples. Does not react with Canine or Chicken. The MA5-13324 immunogen is subcellular fraction of human alveolar macrophages.

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Specifications

• Antigen: CD68
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: P34810
• Gene Symbols: Cd68
• Immunogen: Subcellular fraction of human alveolar macrophages.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Monkey, Feline
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Clone: KP1
• Conjugate: Unconjugated
• Gene: Cd68
• Gene Alias: CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 101099002, 287435, 968
• Content And Storage: 4°C
• Form: Liquid