Invitrogen™ CD68 Monoclonal Antibody (PG-M1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA512407

Catalog No. PIMA512407

Description

MA5-12407 targets CD68 in IHC (P) applications and shows reactivity with Human samples. The MA5-12407 immunogen is gaucher cells.

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Specifications

• Antigen: CD68
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Tissue culture supernatant with 0.09% sodium azide
• Gene Accession No.: P34810
• Gene Symbols: Cd68
• Immunogen: Gaucher cells.
• Regulatory Status: RUO
• Gene ID (Entrez): 968
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Clone: PG-M1
• Conjugate: Unconjugated
• Gene: Cd68
• Gene Alias: CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
• Host Species: Mouse
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG3 κ

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov