CD68 Mouse anti-Human, Clone: 3F7D3, Abnova™

Mouse monoclonal antibody raised against partial recombinant human CD68.

Supplier:  Abnova Corporation MAB12260

Catalog No. 89-933-862

Description

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq]

Specifications

• Antigen: CD68
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Flow Cytometry (1:200-1:400) Immunofluorescence (1:200-1:1000) Immunohistochemistry (1:200-1:1000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Gene Alias: DKFZp686M18236/GP110/SCARD1
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Clone: 3F7D3
• Description: Mouse monoclonal antibody raised against partial recombinant human CD68.
• Formulation: In PBS (0.05% sodium azide)
• Gene Symbols: CD68
• Immunogen: Recombinant protein corresponding to amino acids 42-155 of human CD68.
• Regulatory Status: RUO
• Gene ID (Entrez): 968
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1