CD68 Mouse anti-Human, Clone: 3F7D3, Abnova™

Catalog No.	Quantity
89-933-862	100 μg

Catalog No. 89-933-862 Supplier Abnova Corporation Supplier No. MAB12260

Description

Mouse monoclonal antibody raised against partial recombinant human CD68.

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq]

Specifications

• Antigen: CD68
• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: 3F7D3
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant human CD68.
• Dilution: ELISA (1:10000) Flow Cytometry (1:200-1:400) Immunofluorescence (1:200-1:1000) Immunohistochemistry (1:200-1:1000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: DKFZp686M18236/GP110/SCARD1
• Gene Symbols: CD68
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 42-155 of human CD68.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 968
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1