CD68 Mouse anti-Human, Clone: KP1, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA807199

Catalog No. 50-168-1435

Description

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predomitly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human maligcies, including several Acute Myeloid Leukemia studies.

Specifications

• Antigen: CD68
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CD68
• Gene Alias: GP110, LAMP4, SCARD1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 968
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
• Clone: KP1
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P34810
• Gene Symbols: CD68
• Immunogen: Lysosomal fraction of human lung macrophages CD68(KP1)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1