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CD68 Mouse anti-Human, Clone: LAMP4/824, Abnova™

Catalog No. 89933860 Shop All Abnova Corporation Products
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89-933-860 100 μg
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Catalog No. 89-933-860 Supplier Abnova Corporation Supplier No. MAB13482
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Description

Mouse monoclonal antibody raised against full length recombinant human CD68.

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq]

Specifications

Antigen CD68
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone LAMP4/824
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against full length recombinant human CD68.
Dilution Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS.
Gene Alias DKFZp686M18236/GP110/SCARD1
Gene Symbols CD68
Host Species Mouse
Immunogen Recombinant protein corresponding to full length human CD68.
Purification Method Protein A/G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 968
Target Species Human
Content And Storage Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1 κ
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