CD68 Mouse anti-Human, Clone: OTI6A10, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF803287

Catalog No. 50-166-6409

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predomitly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human maligcies, including several Acute Myeloid Leukemia studies.

Specifications

• Antigen: CD68
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CD68
• Gene Alias: GP110, LAMP4, SCARD1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 968
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI6A10
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P34810
• Gene Symbols: CD68
• Immunogen: Human recombit protein fragment corresponding to amino acids 22-319 of human CD68 produced in SF9 cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b