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Invitrogen™ CD68 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA583940

Catalog No. PIPA583940


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Description

Description

Immunogen sequence: SPTSKETIGD YTWTNGSQPC VHLQAQIQIR VMYTTQGGGE AWGISVLNPN KTKVQGSCEG AHPHLLLSFP YG.

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD68
Polyclonal
Unconjugated
Cd68
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Rabbit
Antigen affinity chromatography
RUO
968
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.10 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P34810
Cd68
Recombinant protein corresponding to Human CD68. Recombinant protein control fragment (Product #RP-100954).
100 μL
Primary
Human
Antibody
IgG
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