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Invitrogen™ CD68 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA583940
Description
Immunogen sequence: SPTSKETIGD YTWTNGSQPC VHLQAQIQIR VMYTTQGGGE AWGISVLNPN KTKVQGSCEG AHPHLLLSFP YG.
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
Specifications
CD68 | |
Polyclonal | |
Unconjugated | |
Cd68 | |
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
968 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.10 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P34810 | |
Cd68 | |
Recombinant protein corresponding to Human CD68. Recombinant protein control fragment (Product #RP-100954). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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