CD68 Rabbit anti-Mouse,Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA578997

Catalog No. PIPA578997

Description

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predomitly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human maligcies, including several Acute Myeloid Leukemia studies.

Specifications

• Antigen: CD68
• Classification: Polyclonal
• Formulation: PBS with 5MG BSA and 0.02% sodium azide, 0.02% thimerosal
• Gene Accession No.: P31996
• Gene Symbols: Cd68
• Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse CD68.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: Cd68
• Gene Alias: Macrosialin, CD68, Cd68
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12514, 287435
• Content And Storage: -20°C
• Form: Lyophilized