Invitrogen™ CD68 Recombinant Mouse Monoclonal Antibody (KP-1)

Mouse Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA544195	Invitrogen™ MA544195	100 μL
PIMA544196	Invitrogen™ MA544196	10 μL

Description

CD68 Recombinant Monoclonal Antibody for IHC (P), Flow

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Specifications

• Antigen: CD68
• Concentration: 50 μg/mL
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 0.1% BSA and 0.09% sodium azide; pH 6.8-7.4
• Gene Accession No.: P34810
• Gene ID (Entrez): 968
• Immunogen: Lysosomal Fraction Of Human Lung Macrophages.
• Product Type: Antibody

• Clone: KP-1
• Content And Storage: 4°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG1
• Target Species: Human
• Gene: Cd68
• Gene Alias: CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
• Gene Symbols: Cd68
• Primary or Secondary: Primary
• Purification Method: Purified