CD68 Mouse anti-Human, Bethyl Laboratories

Catalog No.	Quantity
50-157-1245	100 μL

Catalog No. 50-157-1245 Supplier Bethyl Laboratories, Inc Supplier No. A500018A

Description

Mouse Recombit Monoclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predomitly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human maligcies, including several Acute Myeloid Leukemia studies.

Specifications

• Antigen: CD68
• Applications: Flow Cytometry, Immunohistochemistry
• Classification: Recombinant Monoclonal
• Clone: KP-1
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide
• Gene: CD68
• Gene Accession No.: P34810
• Gene Alias: GP110, LAMP4, SCARD1, CD68 antigen, macrophage antigen CD68, macrosialin, scavenger receptor class D member 1
• Gene Symbols: CD68
• Host Species: Mouse
• Immunogen: Lysosomal fraction of human lung macrophages
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 968
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1