Invitrogen™ CD69 Monoclonal Antibody (H1.2F3)

Armenian Hamster Monoclonal Antibody

Supplier:  Invitrogen™ MA1207

Catalog No. PIMA1207

Description

MA1-207 detects CD69 from human samples. MA1-207 has been successfully tested in western blot, immunofluorescence and flow cytometry applications. In western blot, MA1-207 detects CXCR1/IL8RA (human) at approximate molecular weight of 22.5 kDa.

CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets. In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction. Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants of CD69. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.

Specifications

• Antigen: CD69
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P37217, Q07108
• Gene Symbols: CD69
• Immunogen: Mouse dendritic epidermal T cell line Y245.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: H1.2F3
• Conjugate: Unconjugated
• Gene: CD69
• Gene Alias: 5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen
• Host Species: Armenian Hamster
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 12515, 969
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid