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  6. Invitrogen™ CD69 Monoclonal Antibody (H1.2F3), PE-eFluor™ 610, eBioscience™, Invitrogen™ 

Invitrogen™ CD69 Monoclonal Antibody (H1.2F3), PE-eFluor™ 610, eBioscience™, Invitrogen™
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Catalog No. 61069182
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61-069-182 100 μg
61-069-180 25 μg
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Catalog No. 61-069-182 Supplier Invitrogen™ Supplier No. 61069182
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Description

Armenian Hamster Monoclonal Antibody

The H1.2F3 MAb reacts with mouse CD69, also known as very early activation antigen (VEA). CD69 is approximately 35 kDa and is expressed on the surface as a disulfide-linked dimer. While a small subset of lymphocytes in the thymus, spleen and lymph nodes express this antigen, activation of both T and B cells rapidly upregulates the surface expression of CD69, suggesting a role for CD69 in lymphocyte development and activation.

CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets. In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction. Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants of CD69. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD69
Applications Flow Cytometry
Classification Monoclonal
Clone H1.2F3
Concentration 0.2 mg/mL
Conjugate PE-eFluor 610
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene CD69
Gene Accession No. P37217
Gene Alias 5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen
Gene Symbols CD69
Host Species Armenian Hamster
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12515
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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