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CD7 Antibody (T3-3A1), Novus Biologicals™
SDP

Catalog No. p-5539476 Shop All R&D Systems Products
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0.1 mg
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NBP24480300 0.02 mg
NBP24480301 0.1 mg
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Catalog No. NBP24480300 Supplier Novus Biologicals Supplier No. NBP2448030.02MG
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Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

CD7 Monoclonal specifically detects CD7 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

Antigen CD7
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone T3-3A1
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein
Gene Symbols CD7
Host Species Mouse
Immunogen Human T cells
Molecular Weight of Antigen 40 kDa
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Cytokine Research, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 924
Test Specificity Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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