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CD71 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501726010 Shop All Proteintech Group Inc Products
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50-172-6010 150 μL
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Catalog No. 50-172-6010 Supplier Proteintech Group Inc Supplier No. 100842AP150UL
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Description

Rabbit Polyclonal Antibody

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregcy, irritable bowel syndrome and in HIV patients.

Specifications

Antigen CD71
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TFRC
Gene Accession No. P02786
Gene Alias CD71, p90, sTfR, T9, TFR, TFR1, TFRC, TR, Transferrin receptor protein 1, TRFR
Gene Symbols TFRC
Host Species Rabbit
Immunogen CD71 Fusion Protein Ag0123
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7037
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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