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CD71 Rat anti-Mouse, FITC, Clone: C2, BD

Catalog No. BDB561936 Shop All BD Biosciences Products
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BDB561936 0.1 mg
BDB553266 0.5 mg
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Catalog No. BDB561936 Supplier BD Biosciences Supplier No. 561936
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Description

Rat Monoclonal Antibody

The C2 monoclonal antibody specifically binds to CD71, the transferrin receptor. CD71 is a disulfide-linked homodimer of 95-kDa subunits. CD71 mediates one of the cellular mechanisms for iron uptake, and its expression is regulated according to the cell’s iron requirements. It is expressed at high levels on developing erythroid cells, and it is upregulated after mitogenic activation of B or T lymphocytes. The C2 monoclonal antibody selectivity inhibits some types of T- and B-cell activation by down-regulation of transferrin receptor expression, but it does not block binding of transferrin.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD71
Applications Flow Cytometry
Classification Monoclonal
Clone C2
Concentration 0.5mg/mL
Conjugate FITC
Description Transferrin Receptor; TR; TfR; TfR1; Tfrc; Trfr; Mtvr-1
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse cell line
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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