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Invitrogen™ CD72 Monoclonal Antibody (10.1.D2), FITC
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Catalog No. 501137533
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500 μg
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Catalog No. Quantity
50-113-7533 500 μg
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Catalog No. 50-113-7533 Supplier Invitrogen™ Supplier No. MMCD72101
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Description

Mouse Monoclonal Antibody

CD72 Monoclonal Antibody for Flow

CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD72
Applications Flow Cytometry
Classification Monoclonal
Clone 10.1.D2
Concentration 0.5 mg/mL
Conjugate FITC
Formulation PBS with <0.1% sodium azide; pH 7.4
Gene CD72
Gene Accession No. P21855
Gene Alias B-cell differentiation antigen CD72; CD72; CD72 antigen; Cd72 molecule; CD72b; CD72c; Ly-19; Ly32; Ly-32; LYB2; Lyb-2; Ly-m19; lymphocyte antigen 32; RP11-331F9.9
Gene Symbols CD72
Host Species Mouse
Immunogen Mouse CD72.1 (Lyb-2.1). from DBA/2 mouse spleen cells.
Purification Method Purified
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12517
Target Species Mouse
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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