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Invitrogen™ CD72 Polyclonal Antibody
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Catalog No. PIPA597567
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100 μg
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PIPA597567 100 μg
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Catalog No. PIPA597567 Supplier Invitrogen™ Supplier No. PA597567
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Description

Rabbit Polyclonal Antibody

CD72 Polyclonal Antibody for Western Blot, ICC/IF, ELISA

CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD72
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 3.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene CD72
Gene Accession No. P21854
Gene Alias B-cell differentiation antigen CD72; CD72; CD72 antigen; Cd72 molecule; CD72b; CD72c; Ly-19; Ly32; Ly-32; LYB2; Lyb-2; Ly-m19; lymphocyte antigen 32; RP11-331F9.9
Gene Symbols CD72
Host Species Rabbit
Immunogen Recombinant Human B-cell differentiation antigen CD72 protein (150-208AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 971
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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