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Invitrogen™ CD79a Monoclonal Antibody (HM57)
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Catalog No. PIMA544009
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100 μg
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PIMA544009 100 μg
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Catalog No. PIMA544009 Supplier Invitrogen™ Supplier No. MA544009
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Description

Mouse Monoclonal Antibody

This antibody The antibody HM57 interacts with intracellular domain of CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms.

CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD79a
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone HM57
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene CD79A
Gene Accession No. P11911, P11912, P40293
Gene Alias B-cell antigen receptor; B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule; CD79a molecule, immunoglobulin-associated alpha; CD79A protein; CD79-alpha protein; EGK_10665; Ig alpha; IGA; Igalpha; ig-alpha; immunoglobulin-associated alpha; LOC100913063; Ly54; Ly-54; MB1; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
Gene Symbols CD79A
Host Species Mouse
Immunogen Synthetic peptide corresponding to amino acids 202-216 of human CD79a.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100052219, 100190992, 100724815, 100913063, 12518, 281674, 973
Target Species Human, Mouse, Rat, Rabbit, Bovine, Pig, Horse, Chicken, Guinea Pig, Marsupial
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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