Invitrogen™ CD79a Monoclonal Antibody (HM57), PE

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA516711

Catalog No. PIMA516711

Description

Membrane permeabilization is required for flow cytometry applications. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark. Once reconstituted, this product has a shelf life of approx. 18 months. Mouse anti Human CD79a antibody, clone HM57 recognizes an epitope within the cytoplasmic domain of CD79a.

CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.

Specifications

• Antigen: CD79a
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
• Gene Accession No.: P11911, P11912
• Gene Symbols: CD79A
• Immunogen: Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1.
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Multi-species
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: HM57
• Conjugate: PE
• Gene: CD79A
• Gene Alias: B-cell antigen receptor; B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule; CD79a molecule, immunoglobulin-associated alpha; CD79A protein; CD79-alpha protein; EGK_10665; Ig alpha; IGA; Igalpha; ig-alpha; immunoglobulin-associated alpha; LOC100913063; Ly54; Ly-54; MB1; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100913063, 12518, 973
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Lyophilized