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Invitrogen™ CD79b Monoclonal Antibody (CB3-1), PE, eBioscience™
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Catalog No. 5010477
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100 Tests
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Catalog No. Quantity
50-104-77 100 Tests
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Catalog No. 50-104-77 Supplier Invitrogen™ Supplier No. 12079342
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Description

Mouse Monoclonal Antibody

This CB3-1 monoclonal antibody reacts with human CD79b, the B cell antigen receptor Ig-beta chain. Together with the Ig alpha chain, also known as CD79a, this cell surface molecule forms a heterodimeric complex that associates with membrane immunoglobulin (mIgM). CD79b expression is exclusive to B lymphocytes and B cell lymphomas. Depending on the maturation state of the B cell, CD79b can be expressed either in the cytoplasm or on the cell surface. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation. Applications Reported: This CB3-1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This CB3-1 antibody has been pre-titrated and tested by flow cytometric analysis of normal peripheral blood cells. This can be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD79b is the B cell antigen receptor Ig beta chain (BCR-Ig beta), which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg). The mIgM component binds antigen and the Ig alpha /I g beta heterodimer tranduces signals.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD79b
Applications Flow Cytometry
Classification Monoclonal
Clone CB3-1
Concentration 5 μL/Test
Conjugate PE
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Cd79b
Gene Accession No. P40259
Gene Alias AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; CD79B antigen; CD79b molecule; Cd79b molecule, immunoglobulin-associated beta; Ig beta; IGB; Igbeta; Ig-beta; Immunoglobulin-associated B29 protein; immunoglobulin-associated beta; RP23-418O11.7
Gene Symbols Cd79b
Host Species Mouse
Purification Method Affinity chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 974
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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