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Description
Immunoglobulin (Ig) antigen receptors are composed of a non-covalently- associated complex of Ig and two other proteins, Igα and Igβ, which have been designated in the Fifth International Leukocyte Workshop as CD79a and CD79b respectively. CB3-1 reacts with CD79b, which is expressed on surface Ig(sIg)-positive lymphocytes and B-cell lines but only in the cytoplasm of sIg-negative cells including most terminal deoxynucleotidyl transferase (TdT) positive early pre-B and all cytoplasmic µ positive pre-B cell lines. Antibodies to CD79b are helpful in delineating signal transduction pathways activated via antibody receptors during different stages of B-cell differentiation.
Specifications
Specifications
| Antigen | CD79b |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | CB3-1 |
| Conjugate | PE |
| Description | Igβ |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
| Quantity | 100 Tests |
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For Research Use Only.
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