CD8 beta Antibody (BU88), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2447530.1MG

Catalog No. NBP24475301

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

CD8 beta Monoclonal specifically detects CD8 beta in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

• Antigen: CD8 beta
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
• Gene Alias: CD8 antigen, beta polypeptide 1 (p37), CD8b antigen, CD8b molecule, CD8B1P37, LEU2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T-cell surface glycoprotein CD8 beta chain
• Host Species: Mouse
• Molecular Weight of Antigen: 32 kDa
• Quantity: 0.1 mg
• Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers
• Gene ID (Entrez): 926
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry, Immunofluorescence
• Clone: BU88
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: CD8B
• Immunogen: Human CD8 beta
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: The T cell receptor (TCR) is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (alpha-alpha or alpha-beta) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

For Research Use Only